In vivo validation of thymidylate kinase (TMK) with a rationally designed, selective antibacterial compound.
第一作者:
Thomas A,Keating
第一单位:
AstraZeneca Infection Innovative Medicines, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States. thomas.keating@astrazeneca.com
作者:
医学主题词
抗菌药(Anti-Bacterial Agents);肠球菌属(Enterococcus);革兰氏阳性菌(Gram-Positive Bacteria);革兰氏阳性菌感染(Gram-Positive Bacterial Infections);人类(Humans);模型, 分子(Models, Molecular);核苷一磷酸激酶(Nucleoside-Phosphate Kinase);葡萄球菌感染(Staphylococcal Infections);金黄色葡萄球菌(Staphylococcus aureus)
DOI
10.1021/cb300316n
PMID
22908966
发布时间
2012-11-16
- 浏览16
ACS chemical biology
1866-72页
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