Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency.
第一作者:
Matthew J,Pace
第一单位:
Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America.
作者:
医学主题词
CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);细胞, 培养的(Cells, Cultured);基因表达调控, 病毒(Gene Expression Regulation, Viral);HIV感染(HIV Infections);HIV-1(HIV-1);人类(Humans);白细胞介素17(Interleukin-17);白细胞介素7(Interleukin-7);巨噬细胞炎性蛋白质类(Macrophage Inflammatory Proteins);病毒潜伏期(Virus Latency);病毒复制(Virus Replication);env基因产物, 人免疫缺陷病毒(env Gene Products, Human Immunodeficiency Virus);gag基因产物, 人免疫缺陷病毒(gag Gene Products, Human Immunodeficiency Virus)
DOI
10.1371/journal.ppat.1002818
PMID
22911005
发布时间
2021-10-21
- 浏览13
PLoS pathogens
e1002818页
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