Normal testicular function without detectable follicle-stimulating hormone. A novel mutation in the follicle-stimulating hormone receptor gene leading to apparent constitutive activity and impaired agonist-induced desensitization and internalization.
作者:
主题词
抑制蛋白类(Arrestins);碱基序列(Base Sequence);环AMP(Cyclic AMP);卵泡刺激素(Follicle Stimulating Hormone);基因, 报告(Genes, Reporter);HEK293细胞(HEK293 Cells);人类(Humans);萤光素酶类(Luciferases);男(雄)性(Male);分子序列数据(Molecular Sequence Data);突变(Mutation);表型(Phenotype);受体, FSH(Receptors, FSH);精子发生(Spermatogenesis);睾丸(Testis);转染(Transfection);青年人(Young Adult)
DOI
10.1016/j.mce.2012.08.011
PMID
22954680
发布时间
2013-11-21
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