换一批
换一批Synthesis and evaluation of novel ¹⁸F labeled 2-pyridinylbenzoxazole and 2-pyridinylbenzothiazole derivatives as ligands for positron emission tomography (PET) imaging of β-amyloid plaques.
作者：
主题词
淀粉样β肽类(Amyloid beta-Peptides);动物(Animals);放射自显影术(Autoradiography);苯并噻唑类(Benzothiazoles);苯恶唑类(Benzoxazoles);结合, 竞争性(Binding, Competitive);脑(Brain);药物稳定性(Drug Stability);氟放射性同位素(Fluorine Radioisotopes);人类(Humans);配体(Ligands);男(雄)性(Male);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);肽碎片(Peptide Fragments);斑块, 淀粉样(Plaque, Amyloid);聚乙烯二醇类(Polyethylene Glycols);正电子发射断层显像术(Positron-Emission Tomography);吡啶类(Pyridines);放射配体测定(Radioligand Assay);放射性药物(Radiopharmaceuticals);构效关系(Structure-Activity Relationship);组织分布(Tissue Distribution)
DOI
10.1021/jm300973k
PMID
22974116
发布时间
2022-03-10
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