换一批
换一批4-Oxo-1,4-dihydropyridines as selective CB₂ cannabinoid receptor ligands. Part 2: discovery of new agonists endowed with protective effect against experimental colitis.
作者：
主题词
金刚烷(Adamantane);动物(Animals);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);结合, 竞争性(Binding, Competitive);血蛋白质类(Blood Proteins);CHO细胞(CHO Cells);结肠炎(Colitis);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);人类(Humans);肠吸收(Intestinal Absorption);配体(Ligands);小鼠(Mice);微粒体, 肝(Microsomes, Liver);蛋白质结合(Protein Binding);吡啶类(Pyridines);放射配体测定(Radioligand Assay);受体, 大麻酚, CB2(Receptor, Cannabinoid, CB2);构效关系(Structure-Activity Relationship);三硝基苯磺酸(Trinitrobenzenesulfonic Acid)
DOI
10.1021/jm3008568
PMID
23017078
发布时间
2013-11-21
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