换一批
换一批Perlecan Domain V induces VEGf secretion in brain endothelial cells through integrin α5β1 and ERK-dependent signaling pathways.
第一作者：
Douglas N,Clarke
第一单位：
Department of Molecular & Cellular Medicine, Texas A&M Health Science Center, College Station, Texas, USA.
作者：
主题词
动物(Animals);脑(Brain);丁二烯类(Butadienes);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);色酮类(Chromones);内皮细胞(Endothelial Cells);内皮, 血管(Endothelium, Vascular);酶抑制剂(Enzyme Inhibitors);真核细胞起始因子4E(Eukaryotic Initiation Factor-4E);基因表达调控(Gene Expression Regulation);类肝素硫酸蛋白聚糖类(Heparan Sulfate Proteoglycans);人类(Humans);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);整合素α5β1(Integrin alpha5beta1);MAP激酶信号系统(MAP Kinase Signaling System);小鼠(Mice);吗啉类(Morpholines);腈类(Nitriles);磷酰化(Phosphorylation);蛋白质结构, 三级(Protein Structure, Tertiary);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);受体, 血管内皮生长因子(Receptors, Vascular Endothelial Growth Factor);重组蛋白质类(Recombinant Proteins);血管内皮生长因子A(Vascular Endothelial Growth Factor A)
DOI
10.1371/journal.pone.0045257
PMID
23028886
发布时间
2021-10-21
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