换一批
换一批Structure-activity relationship studies of 4-benzyl-1H-pyrazol-3-yl β-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia.
作者：
主题词
动物(Animals);血糖(Blood Glucose);结晶学, X线(Crystallography, X-Ray);糖尿病, 实验性(Diabetes Mellitus, Experimental);葡糖苷类(Glucosides);人类(Humans);高血糖症(Hyperglycemia);降血糖药(Hypoglycemic Agents);分子构象(Molecular Conformation);大鼠(Rats);钠-葡萄糖转运体1(Sodium-Glucose Transporter 1);钠-葡萄糖转运体2(Sodium-Glucose Transporter 2);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.bmc.2012.09.037
PMID
23062824
发布时间
2018-12-02
- 浏览64
Bioorganic & medicinal chemistry
6598-612页
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