LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets.

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作者： Andreas,Wilm ^[1] ; Pauline Poh Kim,Aw ; Denis,Bertrand ; Grace Hui Ting,Yeo ; Swee Hoe,Ong ; Chang Hua,Wong ; Chiea Chuen,Khor ; Rosemary,Petric ; Martin Lloyd,Hibberd ; Niranjan,Nagarajan

作者单位： Genome Institute of Singapore, 60 Biopolis Street, Genome, #02-01, Singapore 138672, Singapore. ^[1]

主题词计算机模拟(Computer Simulation);登革热病毒(Dengue Virus);大肠杆菌(Escherichia coli);遗传变异(Genetic Variation);基因组学(Genomics);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);突变(Mutation);敏感性与特异性(Sensitivity and Specificity);胃肿瘤(Stomach Neoplasms);病毒蛋白质类(Viral Proteins)

DOI 10.1093/nar/gks918

PMID 23066108

发布时间 2022-04-08

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Nucleic acids research

2012年40卷22期

11189-201页

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LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets.

Nucleic acids research

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Nucleic acids research

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LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets.

Nucleic acids research

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Nucleic acids research

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