换一批
换一批BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression.
作者：
主题词
动物(Animals);抗肿瘤药, 烷基化(Antineoplastic Agents, Alkylating);骨形态发生蛋白质2(Bone Morphogenetic Protein 2);细胞分化(Cell Differentiation);达卡巴嗪(Dacarbazine);减量调节(Down-Regulation);抗药性, 肿瘤(Drug Resistance, Neoplasm);胶质母细胞瘤(Glioblastoma);人类(Humans);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);男(雄)性(Male);小鼠(Mice);肿瘤干细胞(Neoplastic Stem Cells);O(6)-甲基鸟嘌呤DNA甲基转移酶(O(6)-Methylguanine-DNA Methyltransferase);信号传导(Signal Transduction);移植, 异种(Transplantation, Heterologous);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1038/cddis.2012.153
PMID
23076220
发布时间
2022-03-18
- 浏览4
Cell death & disease
e412页
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