换一批
换一批NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.
作者：
主题词
动物(Animals);细胞, 培养的(Cells, Cultured);核心结合因子α2亚基(Core Binding Factor Alpha 2 Subunit);核心结合因子α3亚基(Core Binding Factor Alpha 3 Subunit);基因表达调控, 白血病(Gene Expression Regulation, Leukemic);人类(Humans);Jurkat细胞(Jurkat Cells);白细胞, 单核(Leukocytes, Mononuclear);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);分子靶向治疗(Molecular Targeted Therapy);前体T细胞淋巴母细胞白血病淋巴瘤(Precursor T-Cell Lymphoblastic Leukemia-Lymphoma);蛋白激酶C(Protein Kinase C);活性氧(Reactive Oxygen Species);受体, Notch1(Receptor, Notch1);信号传导(Signal Transduction)
DOI
10.1038/nm.2960
PMID
23086478
发布时间
2025-01-04
- 浏览3
Nature medicine
1693-8页
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