Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening.
第一作者:
Devashish,Kothapalli
第一单位:
Institute for Translational Medicine and Therapeutics, Departments of Pharmacology, Medicine, and Physiology, and the Molecular Profiling Facility, University of Pennsylvania, Philadelphia, PA 19104, USA.
作者:
医学主题词
氨基丙腈(Aminopropionitrile);动物(Animals);主动脉(Aorta);载脂蛋白E3(Apolipoprotein E3);载脂蛋白E类(Apolipoproteins E);动脉粥样硬化(Atherosclerosis);细胞, 培养的(Cells, Cultured);胆固醇, HDL(Cholesterol, HDL);胶原Ⅰ型(Collagen Type I);环氧化酶2(Cyclooxygenase 2);细胞外基质(Extracellular Matrix);细胞外基质蛋白质类(Extracellular Matrix Proteins);纤连蛋白类(Fibronectins);基因表达(Gene Expression);人类(Humans);巨噬细胞(Macrophages);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);微RNAs(MicroRNAs);蛋白赖氨酸6-氧化酶(Protein-Lysine 6-Oxidase)
DOI
10.1016/j.celrep.2012.09.018
PMID
23103162
发布时间
2023-12-13
- 浏览11
Cell reports
1259-71页
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