Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction.

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作者： Alberto,Molano ^[1] ; Zhaofeng,Huang ; Melissa G,Marko ; Angelo,Azzi ; Dayong,Wu ; Elaine,Wang ; Samuel L,Kelly ; Alfred H,Merrill ; Stephen C,Bunnell ; Simin Nikbin,Meydani

作者单位： Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, United States of America. ^[1]

主题词衰老(Aging);动物(Animals);印迹法, 蛋白质(Blotting, Western);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);细胞膜(Cell Membrane);细胞存活(Cell Survival);神经酰胺类(Ceramides);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);鞘脂类(Sphingolipids);突触(Synapses);T淋巴细胞(T-Lymphocytes)

DOI 10.1371/journal.pone.0047650

PMID 23110086

发布时间 2021-10-21

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PloS one

2012年7卷10期

e47650页

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Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction.

PloS one

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PloS one

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Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction.

PloS one

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PloS one

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