Modulation of fatty acid synthase degradation by concerted action of p38 MAP kinase, E3 ligase COP1, and SH2-tyrosine phosphatase Shp2.
第一作者:
Jianxiu,Yu
第一单位:
Department of Biochemistry and Molecular Cell Biology & Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, China. Jianxiu.Yu@gmail.com
作者:
医学主题词
3T3细胞(3T3 Cells);动物(Animals);人类(Humans);脂类代谢(Lipid Metabolism);肝(Liver);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);核蛋白质类(Nuclear Proteins);胰腺(Pancreas);蛋白质酪氨酸磷酸酶, 非受体11型(Protein Tyrosine Phosphatase, Non-Receptor Type 11);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1074/jbc.M112.397885
PMID
23269672
发布时间
2021-10-21
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