换一批Genomic loss of tumor suppressor miRNA-204 promotes cancer cell migration and invasion by activating AKT/mTOR/Rac1 signaling and actin reorganization.
第一作者：
J Saadi,Imam
第一单位：
Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
作者：
医学主题词
肌动蛋白类(Actins);脑源性神经营养因子(Brain-Derived Neurotrophic Factor);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);细胞转化, 肿瘤(Cell Transformation, Neoplastic);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因组, 人(Genome, Human);人类(Humans);微RNAs(MicroRNAs);肿瘤侵润(Neoplasm Invasiveness);肿瘤转移(Neoplasm Metastasis);肿瘤(Neoplasms);蛋白质转运(Protein Transport);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);信号传导(Signal Transduction);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);rac1 GTP结合蛋白质(rac1 GTP-Binding Protein)
DOI
10.1371/journal.pone.0052397
PMID
23285024
发布时间
2022-03-11
基金项目
P30 CA054174/CA/NCI NIH HHS/United States
T32 DK007686/DK/NIDDK NIH HHS/United States
P30 CA054174-17/CA/NCI NIH HHS/United States
- 浏览4
PloS one
e52397页
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