换一批Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance.
第一作者：
Chong Wee,Liew
第一单位：
Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA.
作者：
医学主题词
3T3-L1细胞(3T3-L1 Cells);脂细胞(Adipocytes);青少年(Adolescent);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);动物(Animals);膳食脂肪类(Dietary Fats);女(雌)性(Female);人类(Humans);胰岛素抗药性(Insulin Resistance);脂解作用(Lipolysis);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);中年人(Middle Aged);肥胖症(Obesity);氧化还原(Oxidation-Reduction);受体, 肾上腺素能β3(Receptors, Adrenergic, beta-3);固醇酯酶(Sterol Esterase);产热(Thermogenesis);转录因子(Transcription Factors)
DOI
10.1038/nm.3056
PMID
23291629
发布时间
2024-10-17
基金项目
K99DK090210/DK/NIDDK NIH HHS/United States
R56 DK051586/DK/NIDDK NIH HHS/United States
DK58825/DK/NIDDK NIH HHS/United States
1RL9EB008539-01/EB/NIBIB NIH HHS/United States
R01 DK067536/DK/NIDDK NIH HHS/United States
DK51586/DK/NIDDK NIH HHS/United States
R56 DK058825/DK/NIDDK NIH HHS/United States
R01 HL073168/HL/NHLBI NIH HHS/United States
R01 DK 67536/DK/NIDDK NIH HHS/United States
R00 DK090210/DK/NIDDK NIH HHS/United States
R01 DK051586/DK/NIDDK NIH HHS/United States
K99 DK090210/DK/NIDDK NIH HHS/United States
P30 DK026743/DK/NIDDK NIH HHS/United States
R01 DK058825/DK/NIDDK NIH HHS/United States
RL9 EB008539/EB/NIBIB NIH HHS/United States
P30 DK36836/DK/NIDDK NIH HHS/United States
P30 DK036836/DK/NIDDK NIH HHS/United States
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Nature medicine
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