Unexpected brain lesions in lactating Sprague-Dawley rats in a Two-generation Inhalation Reproductive Toxicity Study with pentafluoropropane (HFC-245fa).
第一作者:
J,Buschmann
第一单位:
Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany. jochen.buschmann@item.fraunhofer.de
作者:
医学主题词
空气污染物(Air Pollutants);动物(Animals);脑(Brain);小脑(Cerebellum);大脑(Cerebrum);剂量效应关系, 药物(Dose-Response Relationship, Drug);女(雌)性(Female);心脏(Heart);烃类, 氟化(Hydrocarbons, Fluorinated);吸入暴露(Inhalation Exposure);泌乳(Lactation);母亲暴露(Maternal Exposure);心肌(Myocardium);坏死(Necrosis);妊娠(Pregnancy);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);存活率分析(Survival Analysis);毒性试验(Toxicity Tests)
DOI
10.1016/j.etp.2012.12.006
PMID
23332645
发布时间
2013-07-08
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