换一批TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila.
第一作者：
Lies,Vanden Broeck
第一单位：
Laboratory of Behavioral and Developmental Genetics, Center of Human Genetics, University of Leuven, B3000 Leuven, Belgium.
作者：
医学主题词
衰老(Aging);动物(Animals);细胞凋亡(Apoptosis);碱基序列(Base Sequence);细胞谱系(Cell Lineage);细胞形状(Cell Shape);DNA结合蛋白质类(DNA-Binding Proteins);黑腹果蝇(Drosophila melanogaster);基因表达谱(Gene Expression Profiling);基因表达调控, 发育期(Gene Expression Regulation, Developmental);基因敲低技术(Gene Knockdown Techniques);基因调控网络(Gene Regulatory Networks);基因, 开关(Genes, Switch);基因型(Genotype);人类(Humans);无脊椎动物激素类(Invertebrate Hormones);变态, 生物学(Metamorphosis, Biological);小鼠(Mice);分子序列数据(Molecular Sequence Data);神经元(Neurons);表型(Phenotype);蛋白质转运(Protein Transport);RNA, 信使(RNA, Messenger);受体, 类固醇(Receptors, Steroid)
DOI
10.1016/j.celrep.2012.12.014
PMID
23333275
发布时间
2025-05-29
- 浏览6
Cell reports
160-72页
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