换一批
换一批Histone deacetylase inhibition attenuates transcriptional activity of mineralocorticoid receptor through its acetylation and prevents development of hypertension.
作者：
主题词
乙酰化作用(Acetylation);醛固酮(Aldosterone);动物(Animals);DNA聚合酶Ⅱ(DNA Polymerase II);脱氧皮质酮(Desoxycorticosterone);疾病模型, 动物(Disease Models, Animal);酶抑制剂(Enzyme Inhibitors);基因表达(Gene Expression);HEK293细胞(HEK293 Cells);组蛋白脱乙酰基酶抑制剂(Histone Deacetylase Inhibitors);组蛋白脱乙酰基酶类(Histone Deacetylases);人类(Humans);高血压, 肾性(Hypertension, Renal);男(雄)性(Male);盐皮质激素类(Mineralocorticoids);肾切除术(Nephrectomy);启动区, 遗传(Promoter Regions, Genetic);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, 盐皮质激素(Receptors, Mineralocorticoid);转录, 遗传(Transcription, Genetic);丙戊酸(Valproic Acid)
DOI
10.1161/CIRCRESAHA.113.301071
PMID
23421989
发布时间
2022-04-08
- 浏览4
Circulation research
1004-12页
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