A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse.

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作者： Francesca,Lugani ^[1] ; Ripla,Arora ; Natalia,Papeta ; Ami,Patel ; Zongyu,Zheng ; Roel,Sterken ; Ruth A,Singer ; Gianluca,Caridi ; Cathy,Mendelsohn ; Lori,Sussel ; Virginia E,Papaioannou ; Ali G,Gharavi

作者单位： Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, United States of America. ^[1]

主题词动物(Animals);DNA结合蛋白质类(DNA-Binding Proteins);胚胎发育(Embryonic Development);基因表达调控, 发育期(Gene Expression Regulation, Developmental);人类(Humans);中胚层(Mesoderm);小鼠(Mice);诱变, 插入(Mutagenesis, Insertional);胰腺(Pancreas);反转录因子(Retroelements);脊髓(Spinal Cord);尾(Tail);转录因子(Transcription Factors)

DOI 10.1371/journal.pgen.1003206

PMID 23437001

发布时间 2021-10-21

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PLoS genetics

2013年9卷2期

e1003206页

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A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse.

PLoS genetics

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PLoS genetics

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A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse.

PLoS genetics

相似文献

PLoS genetics

相关期刊

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