Developmental changes in the expression and function of cytochrome P450 3A isoforms: evidence from in vitro and in vivo investigations.
第一作者:
Ibrahim,Ince
第一单位:
Department of Pediatric Surgery and Intensive Care, Erasmus MC-Sophia Children's Hospital, Dr. Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands.
作者:
医学主题词
成年人(Adult);年龄因素(Age Factors);儿童(Child);细胞色素P-450 CYP3A(Cytochrome P-450 CYP3A);剂量效应关系, 药物(Dose-Response Relationship, Drug);人类(Humans);婴儿(Infant);婴儿, 新生(Infant, Newborn);同工酶类(Isoenzymes);模型, 生物学(Models, Biological);药用制剂(Pharmaceutical Preparations);诊疗准则(主题)(Practice Guidelines as Topic)
DOI
10.1007/s40262-013-0041-1
PMID
23463352
发布时间
2021-10-21
- 浏览6
Clinical pharmacokinetics
333-45页
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