换一批
换一批Improving oral bioavailability and pharmacokinetics of liposomal metformin by glycerolphosphate-chitosan microcomplexation.
作者：
主题词
黏着性(Adhesiveness);投药, 口服(Administration, Oral);动物(Animals);曲线下面积(Area Under Curve);生物利用度(Biological Availability);量热法, 差式扫描(Calorimetry, Differential Scanning);化学, 药物(Chemistry, Pharmaceutical);壳聚糖(Chitosan);迟效制剂(Delayed-Action Preparations);药物载体(Drug Carriers);胃黏膜(Gastric Mucosa);甘油磷酸酯类(Glycerophosphates);降血糖药(Hypoglycemic Agents);肠吸收(Intestinal Absorption);肠黏膜(Intestinal Mucosa);脂质体(Liposomes);男(雄)性(Male);二甲双胍(Metformin);显微镜检查, 电子, 扫描(Microscopy, Electron, Scanning);显微镜检查, 电子, 透射(Microscopy, Electron, Transmission);大鼠(Rats);大鼠, Wistar(Rats, Wistar);流变学(Rheology);溶解度(Solubility);工艺学, 制药(Technology, Pharmaceutical);X线衍射(X-Ray Diffraction)
DOI
10.1208/s12249-013-9926-4
PMID
23471836
发布时间
2021-10-21
- 浏览6
AAPS PharmSciTech
485-96页
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