Clinical scale electroloading of mature dendritic cells with melanoma whole tumor cell lysate is superior to conventional lysate co-incubation in triggering robust in vitro expansion of functional antigen-specific CTL.
第一作者:
Lawrence A,Wolfraim
第一单位:
MaxCyte, Inc., Gaithersburg, MD 20878, USA.
作者:
主题词
抗原呈递(Antigen Presentation);抗原, 肿瘤(Antigens, Neoplasm);癌症疫苗(Cancer Vaccines);细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);共同培养技术(Coculture Techniques);树突细胞(Dendritic Cells);电穿孔(Electroporation);可行性研究(Feasibility Studies);人类(Humans);免疫疗法, 过继(Immunotherapy, Adoptive);干扰素γ(Interferon-gamma);淋巴细胞活化(Lymphocyte Activation);黑色素瘤(Melanoma);T淋巴细胞, 细胞毒性(T-Lymphocytes, Cytotoxic)
DOI
10.1016/j.intimp.2013.01.009
PMID
23474736
发布时间
2020-12-15
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