Protein malnutrition induces bone marrow mesenchymal stem cells commitment to adipogenic differentiation leading to hematopoietic failure.
第一单位:
Department of Clinical and Toxicological Analyses, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
作者:
主题词
脂细胞(Adipocytes);成脂分化(Adipogenesis);动物(Animals);体重(Body Weight);骨髓细胞(Bone Marrow Cells);CCAAT增强子结合蛋白类(CCAAT-Enhancer-Binding Proteins);膳食(Diet);膳食蛋白质类(Dietary Proteins);进食(Eating);成纤维细胞(Fibroblasts);粒细胞巨噬细胞集落刺激因子(Granulocyte-Macrophage Colony-Stimulating Factor);血细胞生成(Hematopoiesis);白细胞介素3(Interleukin-3);男(雄)性(Male);间质干细胞(Mesenchymal Stem Cells);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);PPARγ(PPAR gamma);蛋白质能量营养不良(Protein-Energy Malnutrition);血清白蛋白(Serum Albumin);胆固醇调节元件结合蛋白质类(Sterol Regulatory Element Binding Proteins)
DOI
10.1371/journal.pone.0058872
PMID
23516566
发布时间
2021-10-21
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