换一批Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer.
第一作者：
Elena,Castro
第一单位：
Spanish National Cancer Research Centre 3, Melchor Fernández Almagro, Madrid, Spain.
作者：
医学主题词
成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);抗肿瘤药, 激素(Antineoplastic Agents, Hormonal);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);BRCA1蛋白质(BRCA1 Protein);BRCA2蛋白质(BRCA2 Protein);近距离放射疗法(Brachytherapy);随访研究(Follow-Up Studies);疾病遗传易感性(Genetic Predisposition to Disease);生殖细胞系突变(Germ-Line Mutation);杂合子(Heterozygote);人类(Humans);Kaplan-Meiers评估(Kaplan-Meier Estimate);淋巴结(Lymph Nodes);淋巴转移(Lymphatic Metastasis);男(雄)性(Male);中年人(Middle Aged);肿瘤分期(Neoplasm Staging);列线图(Nomograms);姑息疗法(Palliative Care);表型(Phenotype);试验预期值(Predictive Value of Tests);预后(Prognosis);比例危险度模型(Proportional Hazards Models);前列腺切除术(Prostatectomy);前列腺肿瘤(Prostatic Neoplasms);放射疗法, 辅助(Radiotherapy, Adjuvant);回顾性研究(Retrospective Studies);危险性评估(Risk Assessment);危险因素(Risk Factors)
DOI
10.1200/JCO.2012.43.1882
PMID
23569316
发布时间
2025-05-29
- 浏览46
Journal of clinical oncology
1748-57页
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