换一批
换一批AMP-activated protein kinase negatively regulates FcεRI-mediated mast cell signaling and anaphylaxis in mice.
作者：
关键词
ACCAICARAMP-activated protein kinaseAMPKAcetyl-CoA carboxylaseActivator 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranosideBMMCBone marrow–derived mast cellCA-AMPKCatalytically active AMPKα2ERKExtracellular signal-regulated kinaseFynGRB2-associated-binding protein 2Gab2HSAHuman serum albuminIKKIκB kinaseJNKLKB1LTC(4)Leukotriene C(4)Liver kinase B1MAPKMammalian target of rapamycinMast cellMitogen-activated protein kinaseNF-κBNuclear factor κBPCAPGD(2)PLCγPSAPassive cutaneous anaphylaxisPassive systemic anaphylaxisPhospholipase CγProstaglandin D(2)Small interfering RNASpleen tyrosine kinaseSykWTWild-typeanaphylaxisc-Jun N-terminal kinaseliver kinase B1mTORsiRNAβ-Hexβ-Hexosaminidase
主题词
AMP活化蛋白激酶类(AMP-Activated Protein Kinases);过敏反应(Anaphylaxis);动物(Animals);肥大细胞(Mast Cells);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);原癌基因蛋白质c-fyn(Proto-Oncogene Proteins c-fyn);受体, IgE(Receptors, IgE)
DOI
10.1016/j.jaci.2013.02.018
PMID
23587332
发布时间
2021-12-03
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