换一批
换一批Genistein inhibits TNF-α-induced endothelial inflammation through the protein kinase pathway A and improves vascular inflammation in C57BL/6 mice.
作者：
关键词
5,5-dimethylpyrroline-N-oxideCATCXCL1/KCDMPOEPREREndothelial cellsFBSGPxGRGSHGSTGenisteinHUVECsICAM-1IL-8MCP-1MCP-1/JEPKAPTKProtein kinase AROSSODTNF-αVCAM-1Vascular inflammationcatalasechemokine (C-X-C motif) ligand 1electron paramagnetic resonanceestrogen receptorfetal bovine serumglutathioneglutathione peroxidaseglutathione reductaseglutathione transferasehuman umbilical vein endothelial cellsintercellular adhesion molecule-1interleukin-8monocyte chemotactic protein-1mouse/monocyte chemotactic protein-1/JEprotein kinase Aprotein tyrosin kinasereactive oxygen speciessE-SelectinsICAM-1sVCAM-1soluble E-Selectinsoluble intercellular adhesion molecule-1soluble vascular adhesion molecule-1superoxide dismutasetumor necrosis factor-αvascular adhesion molecule-1
主题词
动物(Animals);环AMP依赖性蛋白激酶类(Cyclic AMP-Dependent Protein Kinases);内皮细胞(Endothelial Cells);内皮, 血管(Endothelium, Vascular);染料木黄酮(Genistein);炎症(Inflammation);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);蛋白激酶抑制剂(Protein Kinase Inhibitors);信号传导(Signal Transduction);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1016/j.ijcard.2013.03.035
PMID
23587398
发布时间
2021-10-21
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