Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts.

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作者： Adam C,Midgley ^[1] ; Mathew,Rogers ; Maurice B,Hallett ; Aled,Clayton ; Timothy,Bowen ; Aled O,Phillips ; Robert,Steadman

作者单位： Institute of Nephrology, School of Medicine and Cardiff Institute of Tissue Engineering and Repair, University of Cardiff, Heath Park, Cardiff CF14 4XN, United Kingdom. ^[1]

关键词 CD44 Epidermal Growth Factor Receptor (EGFR)Hyaluronate Lipid Raft Myofibroblast

主题词钙-钙调素依赖性蛋白激酶2型(Calcium-Calmodulin-Dependent Protein Kinase Type 2);细胞分化(Cell Differentiation);细胞系, 转化(Cell Line, Transformed);酶激活(Enzyme Activation);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);葡糖醛酸基转移酶(Glucuronosyltransferase);人类(Humans);透明质酸(Hyaluronic Acid);膜微区(Membrane Microdomains);肌成纤维细胞(Myofibroblasts);信号传导(Signal Transduction);Smad蛋白质类(Smad Proteins);转化生长因子β1(Transforming Growth Factor beta1);伤口愈合(Wound Healing)

DOI 10.1074/jbc.M113.451336

PMID 23589287

发布时间 2022-03-31

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The Journal of biological chemistry

2013年288卷21期

14824-38页

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Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts.

The Journal of biological chemistry

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The Journal of biological chemistry

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Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts.

The Journal of biological chemistry

相似文献

The Journal of biological chemistry

相关期刊

检索历史清除