Artificial extracellular matrix composed of collagen I and highly sulfated hyaluronan interferes with TGFβ(1) signaling and prevents TGFβ(1)-induced myofibroblast differentiation.
第一作者:
Anja,van der Smissen
第一单位:
Department of Dermatology, Venereology and Allergology, Leipzig University, 04103 Leipzig, Germany. anja.vandersmissen@medizin.uni-leipzig.de
作者:
主题词
仿生材料(Biomimetic Materials);细胞分化(Cell Differentiation);细胞, 培养的(Cells, Cultured);胶原Ⅰ型(Collagen Type I);细胞外基质(Extracellular Matrix);人类(Humans);透明质酸(Hyaluronic Acid);材料试验(Materials Testing);肌成纤维细胞(Myofibroblasts);信号传导(Signal Transduction);硫酸盐类(Sulfates);表面特性(Surface Properties);转化生长因子β1(Transforming Growth Factor beta1)
DOI
10.1016/j.actbio.2013.04.023
PMID
23602877
发布时间
2013-07-01
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Acta biomaterialia
7775-86页
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