Compartmentalized oxidative stress in dopaminergic cell death induced by pesticides and complex I inhibitors: distinct roles of superoxide anion and superoxide dismutases.

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作者： Humberto,Rodriguez-Rocha ^[1] ; Aracely,Garcia-Garcia ^[1] ; Chillian,Pickett ^[1] ; Sumin,Li ^[1] ; Jocelyn,Jones ^[2] ; Han,Chen ^[3] ; Brian,Webb ^[4] ; Jae,Choi ^[4] ; You,Zhou ^[5] ; Matthew C,Zimmerman ^[6] ; Rodrigo,Franco ^[7]

作者单位： Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68583-0905, USA; School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583-0905, USA. ^[1] Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE 68198-5850, USA. ^[2] Center for Biotechnology, University of Nebraska-Lincoln, Lincoln, NE 68583-0905, USA. ^[3] Thermo Scientific, Research and Development, Rockford, IL 61105, USA. ^[4] Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68583-0905, USA; School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583-0905, USA; Center for Biotechnology, University of Nebraska-Lincoln, Lincoln, NE 68583-0905, USA. ^[5] Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68583-0905, USA; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE 68198-5850, USA. ^[6] Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68583-0905, USA; School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583-0905, USA. Electronic address: rfrancocruz2@unl.edu. ^[7]

关键词 CuZnSOD Environmental MPP+MnSOD Paraquat Parkinson's disease Pesticides Porphyrins Rotenone SOD roGFP