首页> BMC medical genomics> A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation.

A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation.

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第一作者： Yi,Zhang

第一单位： TOPS Obesity and Metabolic Research Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. yzhang@mcw.edu

作者： Yi,Zhang ^[1] ; Jack W,Kent ; Michael,Olivier ; Omar,Ali ; Diana,Cerjak ; Ulrich,Broeckel ; Reham M,Abdou ; Thomas D,Dyer ; Anthony,Comuzzie ; Joanne E,Curran ; Melanie A,Carless ; David L,Rainwater ; Harald H H,Göring ; John,Blangero ; Ahmed H,Kissebah

作者单位： TOPS Obesity and Metabolic Research Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. yzhang@mcw.edu ^[1]

医学主题词 A型激酶锚定蛋白质类(A Kinase Anchor Proteins);脂联素(Adiponectin);碱性螺旋-环-螺旋转录因子类(Basic Helix-Loop-Helix Transcription Factors);钙黏着糖蛋白类(Cadherins);细胞转化, 肿瘤(Cell Transformation, Neoplastic);染色体, 人, 14对(Chromosomes, Human, Pair 14);染色体, 人, 5对(Chromosomes, Human, Pair 5);基因型(Genotype);单倍型(Haplotypes);人类(Humans);炎症(Inflammation);白细胞(Leukocytes);肌球蛋白类(Myosins);神经组织蛋白质类(Nerve Tissue Proteins);表型(Phenotype);多态性, 单核苷酸(Polymorphism, Single Nucleotide);数量性状基因座位(Quantitative Trait Loci);RNA, 信使(RNA, Messenger);转录因子(Transcription Factors)

DOI 10.1186/1755-8794-6-14

PMID 23628382

发布时间 2023-11-04

基金项目

S10 RR029392/RR/NCRR NIH HHS/United States DK071895-03/DK/NIDDK NIH HHS/United States DK65598-01/DK/NIDDK NIH HHS/United States UL1 TR000055/TR/NCATS NIH HHS/United States R37 MH059490/MH/NIMH NIH HHS/United States

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