换一批
换一批Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction.
第一作者：
So Hee,Jin
第一单位：
College of Pharmacy, Chosun University, Gwangju 501-759, South Korea.
作者：
关键词
ACCAMP-activated protein kinaseAMPKAcetyl-CoA carboxylaseDN-AMPKDominant-negative AMP-activated protein kinaseFASFXRFarnesoid X receptorFatty acid synthaseGSHHFDHepatic lipogenesisHigh-fat dietLXRELXRαLiver X receptor elementsLiver X receptor- αLiver X receptor-αNAFLDNASHNF-E2-related factor 2Nonalcoholic fatty liver diseaseNonalcoholic steatohepatitisNrf2PXRROSRXRReactive oxygen speciesResveratrolRetinoid X receptorSCD-1SREBP-1cSesnSestrinSirt1Sirtuin 1Stearoyl-CoA desaturase-1Sterol regulatory element binding protein-1cT090T0901317glutathionepregnane X receptor
主题词
动物(Animals);抗氧化剂(Antioxidants);细胞周期蛋白质类(Cell Cycle Proteins);基因敲低技术(Gene Knockdown Techniques);热休克蛋白质类(Heat-Shock Proteins);Hep G2细胞(Hep G2 Cells);人类(Humans);烃类, 氟化(Hydrocarbons, Fluorinated);脂肪生成(Lipogenesis);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 近交ICR(Mice, Inbred ICR);核蛋白质类(Nuclear Proteins);孤儿核受体(Orphan Nuclear Receptors);过氧化物酶类(Peroxidases);蛋白质类(Proteins);RNA, 小分子干扰(RNA, Small Interfering);胆固醇调节元件结合蛋白质1(Sterol Regulatory Element Binding Protein 1);二苯乙烯类(Stilbenes);磺胺类(Sulfonamides);增量调节(Up-Regulation)
DOI
10.1016/j.taap.2013.04.023
PMID
23651738
发布时间
2022-06-24
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