Uncoupling protein 2 deficiency mimics the effects of hypoxia and endoplasmic reticulum stress on mitochondria and triggers pseudohypoxic pulmonary vascular remodeling and pulmonary hypertension.
作者:
主题词
动物(Animals);细胞, 培养的(Cells, Cultured);高血压, 肺性(Hypertension, Pulmonary);离子通道(Ion Channels);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);线粒体(Mitochondria);线粒体蛋白质类(Mitochondrial Proteins);分子模拟(Molecular Mimicry);肌细胞, 平滑肌(Myocytes, Smooth Muscle);肺动脉(Pulmonary Artery);随机分配(Random Allocation)
DOI
10.1161/CIRCRESAHA.112.300699
PMID
23652801
发布时间
2016-11-25
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Circulation research
126-36页
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