换一批Frequency of acute myeloid leukaemia-associated mouse chromosome 2 deletions in X-ray exposed immature haematopoietic progenitors and stem cells.
第一作者：
C-H,Olme
第一单位：
Cancer Genetics and Cytogenetics Group, Biological Effects Department, Centre for Radiation Chemical and Environmental Hazards, Public Health England, Didcot, Oxfordshire OX11 ORQ, United Kingdom.
作者：
关键词
7-AAD7-aminoactinomycin DBAC-FISHBMCsCFU-S12CMPCSCChromosome deletionGFPHSCIMDMIRIscove's modified Dulbecco's mediumLSKLin(?)Lin(?) Sca-1(+) c-Kit(+)MEPMMPMouse modelMyeloid leukaemiaRadiationSfpi1(GFP/+)Sfpi1(GFP/GFP)Sfpi1/PU.1Stem cellsbacterial artificial chromosome-fluorescent in situ hybridisationbone marrow cellscancer stem cellcolony forming unit spleen on day 12common myeloid progenitordel2green fluorescent proteinhaematopoietic stem cellheterozygous for the Sfpi1-GFP reporter genehomozygous for the Sfpi1-GFP reporter geneinterstitial deletion of chromosome 2ionising radiationlineage negative immature bone marrow cellsmulti-potent progenitormyeloid-erythroid progenitorrAMLradiation-induced acute myeloid leukaemia
医学主题词
动物(Animals);抗原, Ly(Antigens, Ly);骨髓(Bone Marrow);细胞谱系(Cell Lineage);细胞, 培养的(Cells, Cultured);染色体缺失(Chromosome Deletion);染色体(Chromosomes);流式细胞术(Flow Cytometry);绿色荧光蛋白质类(Green Fluorescent Proteins);造血干细胞(Hematopoietic Stem Cells);免疫磁化分离(Immunomagnetic Separation);原位杂交, 荧光(In Situ Hybridization, Fluorescence);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);膜蛋白质类(Membrane Proteins);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 近交CBA(Mice, Inbred CBA);原癌基因蛋白质类c-kit(Proto-Oncogene Proteins c-kit);X线(X-Rays)
DOI
10.1016/j.mrgentox.2013.04.018
PMID
23665297
发布时间
2025-06-08
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Mutation research
119-26页
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