Differential androgen deprivation therapies with anti-androgens casodex/bicalutamide or MDV3100/Enzalutamide versus anti-androgen receptor ASC-J9(R) Lead to promotion versus suppression of prostate cancer metastasis.
作者:
主题词
雄激素受体拮抗剂(Androgen Receptor Antagonists);雄激素类(Androgens);酰苯胺类(Anilides);动物(Animals);苯甲酰胺类(Benzamides);细胞系, 肿瘤(Cell Line, Tumor);姜黄素(Curcumin);减量调节(Down-Regulation);基因表达调控, 酶学(Gene Expression Regulation, Enzymologic);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);男(雄)性(Male);基质金属蛋白酶9(Matrix Metalloproteinase 9);小鼠(Mice);小鼠, 裸(Mice, Nude);肿瘤侵润(Neoplasm Invasiveness);肿瘤转移(Neoplasm Metastasis);肿瘤蛋白质类(Neoplasm Proteins);肿瘤移植(Neoplasm Transplantation);肿瘤, 实验性(Neoplasms, Experimental);腈类(Nitriles);苯硫乙内酰脲(Phenylthiohydantoin);前列腺特异抗原(Prostate-Specific Antigen);前列腺肿瘤(Prostatic Neoplasms);Smad3蛋白质(Smad3 Protein);甲苯磺酰化合物(Tosyl Compounds);转化生长因子β1(Transforming Growth Factor beta1);移植, 异种(Transplantation, Heterologous);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1074/jbc.M113.477216
PMID
23687298
发布时间
2021-12-03
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