换一批
第一作者：
Catia,Lambertucci
第一单位：
School of Pharmacy, Medicinal Chemistry Unit, University of Camerino, Via S. Agostino, 1, 62032 Camerino, MC, Italy.
作者：
关键词
2′,3′-O-(2,4,6-trinitrophenyl)-ATPATPAdenine derivativesCPUDCMDRGHTSHill coefficientMOEMolecular Operating EnvironmentNOEP2X3 receptorP2X3 receptor antagonistsPPADSPPPPTLCPTSAPatch clampPurinePurine derivativesPurinergic receptorsTBANTEATFAATGTLCTNP-ATPcentral processing unitdichloromethanedorsal root ganglionhigh-throughput screeningn(H)nuclear Overhauser effectp-toluenesulfonic acidpreparative thin-layer chromatographypyridoxalphosphate-6-azophenyl-2′,4′-disulfonic acidrise timetetrabutylammonium nitratethin-layer chromatographytime constant of desensitization decaytriethylaminetrifluoroacetic anhydridetrigeminal gangliatriphosphateα,β-meATPα,β-methyleneATPτ(des1;2)τ(on)
医学主题词
腺嘌呤(Adenine);动物(Animals);剂量效应关系, 药物(Dose-Response Relationship, Drug);HEK293细胞(HEK293 Cells);人类(Humans);小鼠(Mice);模型, 分子(Models, Molecular);分子结构(Molecular Structure);大鼠(Rats);受体, 嘌呤能P2X3(Receptors, Purinergic P2X3);重组蛋白质类(Recombinant Proteins);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.ejmech.2013.04.037
PMID
23688699
发布时间
2025-05-29
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