Histone demethylase KDM4C regulates sphere formation by mediating the cross talk between Wnt and Notch pathways in colonic cancer cells.
第一作者:
Shinzo,Yamamoto
第一单位:
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
作者:
医学主题词
动物(Animals);钙结合蛋白质类(Calcium-Binding Proteins);细胞系, 肿瘤(Cell Line, Tumor);结直肠肿瘤(Colorectal Neoplasms);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);含Jumonji结构域组蛋白脱甲基酶类(Jumonji Domain-Containing Histone Demethylases);膜蛋白质类(Membrane Proteins);小鼠(Mice);模型, 生物学(Models, Biological);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);受体, Notch(Receptors, Notch);信号传导(Signal Transduction);球形体, 细胞(Spheroids, Cellular);肿瘤负荷(Tumor Burden);肿瘤细胞, 培养的(Tumor Cells, Cultured);Wnt蛋白质类(Wnt Proteins);β连环素(beta Catenin)
DOI
10.1093/carcin/bgt174
PMID
23698634
发布时间
2016-11-25
- 浏览29
Carcinogenesis
2380-8页
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