Uric acid induces oxidative stress and growth inhibition by activating adenosine monophosphate-activated protein kinase and extracellular signal-regulated kinase signal pathways in pancreatic β cells.
第一作者:
Yongneng,Zhang
第一单位:
Department of Internal Medicine, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
作者:
主题词
腺苷酸激酶(Adenylate Kinase);动物(Animals);阴离子转运蛋白质类(Anion Transport Proteins);细胞系(Cell Line);细胞增殖(Cell Proliferation);酶激活(Enzyme Activation);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);基因表达(Gene Expression);葡萄糖(Glucose);高尿酸血症(Hyperuricemia);胰岛素(Insulin);胰岛素分泌细胞(Insulin-Secreting Cells);MAP激酶信号系统(MAP Kinase Signaling System);氧化性应激(Oxidative Stress);磷酰化(Phosphorylation);蛋白质加工, 转译后(Protein Processing, Post-Translational);大鼠(Rats);尿酸(Uric Acid)
DOI
10.1016/j.mce.2013.04.027
PMID
23707617
发布时间
2022-03-16
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