Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter.
作者:
主题词
抗体(Antibodies);病例对照研究(Case-Control Studies);因子Ⅷ(Factor VIII);血红素加氧酶-1(Heme Oxygenase-1);血友病A(Hemophilia A);人类(Humans);微卫星重复(Microsatellite Repeats);多态性, 单核苷酸(Polymorphism, Single Nucleotide);启动区, 遗传(Promoter Regions, Genetic);疾病严重程度指数(Severity of Illness Index)
DOI
10.3324/haematol.2013.084665
PMID
23716558
发布时间
2021-10-21
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Haematologica
1650-5页
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