Protective effect of zinc supplementation against cadmium-induced oxidative stress and the RANK/RANKL/OPG system imbalance in the bone tissue of rats.
第一作者:
Malgorzata M,Brzóska
第一单位:
Department of Toxicology, Medical University of Bialystok, Adama Mickiewicza 2C Street, 15-222 Bialystok, Poland. Electronic address: Malgorzata.Brzoska@umb.edu.pl.
作者:
关键词
8-OHdG8-hydroxy-2′-deoxyguanosineBMDBone tissueCATCTXCadmiumCdCuFeGPxGRGSHH(2)O(2)LPOMnOCOPGOSIOxidative stressP-SHPCProtectionRANK/RANKL/OPG systemROSSODT-SHTASTOSZincZnbone mineral densitycadmiumcarboxy-terminal cross-linking telopeptides of type I collagencatalasecopperglutathione peroxidaseglutathione reductasehydrogen peroxideironlipid peroxidesmanganeseosteocalcinosteoprotegerinoxidative stress indexprotein carbonyl groupsprotein thiol groupsreactive oxygen speciesreduced glutathionesRANKLsRANKL/OPGsoluble receptor activator of nuclear factor-κΒsuperoxide dismutasethe ratio of sRANKL and OPGtotal antioxidative statustotal oxidative statustotal thiol groupszinc
医学主题词
方差分析(Analysis of Variance);动物(Animals);抗氧化剂(Antioxidants);骨和骨组织(Bone and Bones);氯化镉(Cadmium Chloride);氯化物(Chlorides);DNA损伤(DNA Damage);营养保健品(Dietary Supplements);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);脂类代谢(Lipid Metabolism);男(雄)性(Male);NF-κB(NF-kappa B);骨保护素(Osteoprotegerin);氧化性应激(Oxidative Stress);RANK配体(RANK Ligand);大鼠(Rats);大鼠, Wistar(Rats, Wistar);锌化合物(Zinc Compounds)
DOI
10.1016/j.taap.2013.05.016
PMID
23726800
发布时间
2013-11-21
- 浏览148
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文


换一批



