The metastasis-associated molecule C4.4A promotes tissue invasion and anchorage independence by associating with the alpha6beta4 integrin.
作者:
关键词
ASML-C4.4AkdASMLwtBSp73ASMLC4.4AC4.4A shRNA transfected ASML cellsGPIIPLN111/LN332LN332Laminin 332MMP-Inh.IIMMP14MMP9/13-Inhibitor-II, WB: Western blotMetastasisPI3K/Aktalpha6beta4concentrated serum-free and vesicle-depleted culture supernatant of 804G cellsformerly laminin 1 and 5glycosyl-phosphatidyl inositolimmunoprecipitationmembrane type 1 matrix metalloproteinaseα6β4α6β4 integrin
主题词
动物(Animals);细胞凋亡(Apoptosis);细胞黏附分子(Cell Adhesion Molecules);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);顺铂(Cisplatin);女(雌)性(Female);流式细胞术(Flow Cytometry);荧光抗体技术(Fluorescent Antibody Technique);GPI连接蛋白质类(GPI-Linked Proteins);免疫组织化学(Immunohistochemistry);整合素α6β4(Integrin alpha6beta4);层黏连蛋白(Laminin);基质金属蛋白酶14(Matrix Metalloproteinase 14);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);大鼠(Rats)
DOI
10.1016/j.molonc.2013.05.002
PMID
23727360
发布时间
2025-01-14
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Molecular oncology
917-28页
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