Intrachromosomal looping is required for activation of endogenous pluripotency genes during reprogramming.
作者:
主题词
动物(Animals);印迹法, 蛋白质(Blotting, Western);细胞周期蛋白质类(Cell Cycle Proteins);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);染色质(Chromatin);染色质免疫沉淀法(Chromatin Immunoprecipitation);染色体蛋白质类, 非组蛋白(Chromosomal Proteins, Non-Histone);胚胎, 哺乳动物(Embryo, Mammalian);增强子元件, 遗传学(Enhancer Elements, Genetic);后成说, 遗传(Epigenesis, Genetic);成纤维细胞(Fibroblasts);流式细胞术(Flow Cytometry);绿色荧光蛋白质类(Green Fluorescent Proteins);诱导多能干细胞(Induced Pluripotent Stem Cells);小鼠(Mice);八聚体转录因子3(Octamer Transcription Factor-3);启动区, 遗传(Promoter Regions, Genetic);RNA, 信使(RNA, Messenger);RNA, 小分子干扰(RNA, Small Interfering);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction)
DOI
10.1016/j.stem.2013.05.012
PMID
23747202
发布时间
2016-05-18
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Cell stem cell
30-5页
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