Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations.
第一作者:
João,Mello-Vieira
第一单位:
Centro de Química-Física Molecular and Institute of Nanoscience and Nanotechnology, IST, UTL, Lisbon, Portugal.
作者:
关键词
1,2-dioleoyl-sn-glicero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl)1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(nitro-2-1,3-benzoxadiazol-4yl)1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-biotinyl1,6-diphenyl-1,3,5-hexatriene1-(4-Trimethylammoniumphenyl)-6-phenyl-1,3,5-hexatriene p-toluenesulfonate1-[2-Hydroxy-3-(N,N-di-methyl-N-hydroxyethyl)ammoniopropyl]-4-[β-[2-(di-n-butylamino)-6-napthyl] vinyl]pyridinium dibromide1-palmitoyl-2-oleoyl-sn-glicero-3-phosphorylcholineApoptosisBA(s)BaxBcl-2-associated X proteinBile acid(s)CDCAChenodeoxycholic acidCholCholesterolDCADHEDOPE-RhoDPHDPPE-NBDDPPE-biotinDehydroergosterolDeoxycholic acidFRETFluorescence spectroscopyF?rster resonance energy transferGUVGiant unilamellar vesiclesLUVLarge unilamellar vesiclesLipid raftsLiquid disorderedLiquid orderedModel membrane systemsN-palmitoyl-d-erythro-sphingosylphosphorylcholineNBDPOPCPSMTMA-DPHTUDCATauroursodeoxycholic acidUDCAUrsodeoxycholic aciddi-4-ANEPPDHQl(d)l(o)nitro-2-1,3-benzoxadiazol-4yl
医学主题词
4-氰-7-硝基苯呋咀(4-Chloro-7-nitrobenzofurazan);胆固醇(Cholesterol);脱氧胆酸(Deoxycholic Acid);二苯己三烯(Diphenylhexatriene);荧光共振能量转移(Fluorescence Resonance Energy Transfer);荧光染料(Fluorescent Dyes);脂双层(Lipid Bilayers);磷脂酰胆碱类(Phosphatidylcholines);磷脂酰乙醇胺类(Phosphatidylethanolamines);染色与标记(Staining and Labeling);牛磺鹅脱氧胆酸(Taurochenodeoxycholic Acid);熊脱氧胆酸(Ursodeoxycholic Acid)
DOI
10.1016/j.bbamem.2013.05.021
PMID
23747364
发布时间
2022-03-18
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