换一批IFN-γ inhibits liver progenitor cell proliferation in HBV-infected patients and in 3,5-diethoxycarbonyl-1,4-dihydrocollidine diet-fed mice.
第一作者：
Hong-lei,Weng
第一单位：
Department of Medicine II, Section Molecular Hepatology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
作者：
关键词
3,5-diethoxycarbonyl-1,4-dihydrocollidineALTBMOLBrdUCCl(4)CDECK19CK7Cytokeratin-19Cytokeratin-7DDCDRECMHSCHepatic stellate cellsIHCIHLCIRF-1LPCLPSMPKMacrophagesNK cellNKT cellPCNASTAT1T helper 1Th1alanine aminotransferasebipotential murine oval liverbromodeoxyuridinecarbon tetrachloridecholine deficient, ethionine supplemented dietcytokeratin-19cytokeratin-7ductular reactionextracellular matrixhepatic stellate cellimmunohistochemistryinterferon regulator factor-1intermediate hepatocyte-like celllipopolysaccharideliver progenitor cellsmuscle pyruvate kinasenatural killer T cellnatural killer cellproliferating cell nuclear antigensignal transducer and activator of transcription 1α-SMAα-smooth muscle actin
医学主题词
成体干细胞(Adult Stem Cells);动物(Animals);细胞系(Cell Line);细胞增殖(Cell Proliferation);肝星状细胞(Hepatic Stellate Cells);乙型肝炎, 慢性(Hepatitis B, Chronic);肝细胞(Hepatocytes);人类(Humans);干扰素γ(Interferon-gamma);肝硬化(Liver Cirrhosis);巨噬细胞活化(Macrophage Activation);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);吡啶类(Pyridines);信号传导(Signal Transduction)
DOI
10.1016/j.jhep.2013.05.041
PMID
23747755
发布时间
2025-05-29
- 浏览150
Journal of hepatology
738-45页
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