换一批Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoin.
第一作者：
Silje Z,Krokeide
第一单位：
Department of Microbiology, University of Oslo, Oslo University Hospital, Rikshospitalet, PO Box 4950, Nydalen, NO-0424 Oslo, Norway.
作者：
关键词
2,6-diamino-4-hydroxy-5-formamidopyrimidine5-hydroxy-2′-deoxycytidine5-hydroxy-2′-deoxyuridine5OHC5OHUAPBERBase excision repairCVDNA damageDNA glycosylaseE. coli endonuclease VIIIE. coli endonuclease VIII-likeEscherichia coli formamidopyrimidine DNA glycosylaseFpgGDGhH2THHuman NEIL3MCSMouse Neil3NEILNeiNthOxidationROSSpUDGapurinic/apyrimidinicbase excision repaircolumn volumecore glycosylase domaindouble-strandeddsendonuclease IIIfaPyguanidinohydantoinhelix-two-turn-helixmultiple cloning sitereactive oxygen speciessingle-strandedspiroiminodihydantoinssuracil DNA glycosylase
医学主题词
催化域(Catalytic Domain);DNA(DNA);DNA断裂, 双链(DNA Breaks, Double-Stranded);DNA断裂, 单链(DNA Breaks, Single-Stranded);DNA糖基化酶类(DNA Glycosylases);DNA修复(DNA Repair);胍类(Guanidines);鸟苷(Guanosine);人类(Humans);乙内酰脲类(Hydantoins);赖氨酸(Lysine);突变(Mutation);N-糖基水解酶类(N-Glycosyl Hydrolases);重组蛋白质类(Recombinant Proteins);螺环化合物(Spiro Compounds);底物特异性(Substrate Specificity)
DOI
10.1016/j.dnarep.2013.04.026
PMID
23755964
发布时间
2022-02-23
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DNA repair
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