换一批
换一批The sphingolipid psychosine inhibits fast axonal transport in Krabbe disease by activation of GSK3β and deregulation of molecular motors.
第一单位：
Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
作者：
主题词
方差分析(Analysis of Variance);动物(Animals);动物, 新生(Animals, Newborn);轴突运输(Axonal Transport);细胞, 培养的(Cells, Cultured);大脑皮质(Cerebral Cortex);疾病模型, 动物(Disease Models, Animal);胚胎, 哺乳动物(Embryo, Mammalian);酶抑制剂(Enzyme Inhibitors);基因表达调控, 发育期(Gene Expression Regulation, Developmental);糖原合成酶激酶3(Glycogen Synthase Kinase 3);脑白质营养不良, 球样细胞(Leukodystrophy, Globoid Cell);膜微区(Membrane Microdomains);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 突变型(Mice, Mutant Strains);显微镜检查, 电子, 透射(Microscopy, Electron, Transmission);线粒体(Mitochondria);分子马达蛋白质类(Molecular Motor Proteins);神经组织蛋白质类(Nerve Tissue Proteins);神经元(Neurons);鞘氨醇半乳糖苷(Psychosine);坐骨神经(Sciatic Nerve);时间因素(Time Factors)
DOI
10.1523/JNEUROSCI.0217-13.2013
PMID
23761900
发布时间
2024-03-27
- 浏览18
The Journal of neuroscience
10048-56页
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