换一批Structural elucidation of transmembrane transporter protein bilitranslocase: conformational analysis of the second transmembrane region TM2 by molecular dynamics and NMR spectroscopy.
第一作者：
Amrita,Roy Choudhury
第一单位：
National Institute of Chemistry, Ljubljana, Slovenia. Electronic address: Amrita.RoyChoudhury@ki.si.
作者：
关键词
1,2-dilauroyl-sn-glycero-3-phosphocholine1,2-dimyristoyl-sn-glycero-3-phosphocholine1,2-dioleoyl-sn-glycero-3-phosphocholineABNRAMFAdopted Basis Newton–Raphson methodBTLBilitranslocaseCDCPNNDLPCDMPCDOPCDPCDPPCDSSDrug targetFRETHSQCHeteronuclear Single Quantum Correlation spectroscopyMDMolecular dynamic simulationsNMR spectroscopyRFDSDSDSTAVTM2TM2ATM2BTM3Transmembrane peptidesatomic force microscopybilitranslocase proteincircular dichroismcounter-propagation neural networkdipalmitoyl phosphatidyl cholinedodecylphosphocholinefluorescence resonance energy transfermolecular dynamicspeptide represented third transmembrane region (residues 220–237) of BTL proteinpeptide representing a prolonged second transmembrane segment (positions 73–99) of BTL proteinpeptide representing the second (positions 73–95) transmembrane region of BTL proteinpeptide representing the second (positions 75–94) transmembrane segment of BTL proteinradial distribution functionsodium 2,2-dimethyl-2-silapentane-5-sulfonatesodium dodecyl sulfatesteepest descenttime-averaged distance restraints
医学主题词
氨基酸序列(Amino Acid Sequence);生物转运, 主动(Biological Transport, Active);血浆铜蓝蛋白(Ceruloplasmin);圆二色性(Circular Dichroism);膜蛋白质类(Membrane Proteins);微胶粒(Micelles);分子动力学模拟(Molecular Dynamics Simulation);分子序列数据(Molecular Sequence Data);核磁共振, 生物分子(Nuclear Magnetic Resonance, Biomolecular);蛋白质构象(Protein Conformation);十二烷硫酸钠(Sodium Dodecyl Sulfate)
DOI
10.1016/j.bbamem.2013.06.006
PMID
23774522
发布时间
2024-01-09
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