换一批
换一批Oleanolic acid improves hepatic insulin resistance via antioxidant, hypolipidemic and anti-inflammatory effects.
作者：
关键词
ALTAMP-activated protein kinaseAMPKASTAUCAktDCFDHEDyslipidemiaFBGFFAsG6PGCLGCLcGSHGSSGGlucose-6-phosphataseHDLHDL-cholesterolHepatic insulin resistanceIL-1βIL-6IPGTTIPITTInflammationLDLLDL-cholesterolMMPNrf2OAOleanolic acidPEPCKPGC-1αROSReactive oxygen speciesRho123Rhodamine 123T2DMTBARSTCTEMTGTNFαTZDsarea under the curveaspartate aminotransferasedichlorodihydrofluorescein diacetatedihydroethidiumfasting blood glucosefree fatty acidsglutathioneglutathione (oxidized form)glutathione cysteine ligase catalytic subunitinterleukin-1βinterleukin-6intraperitoneal glucose tolerance testintraperitoneal insulin tolerance testmitochondrial membrane potentialnuclear factor erythroid 2 p45-related factor 2oleanolic acidperoxisome proliferator-activated receptor-γ coactivatorphosphoenolpyruvate carboxykinaseprotein kinase Breactive oxygen speciesserum alanine aminotransferasethiazolidinedionesthiobarbituric acid reactive substancestotal cholesteroltransmission electron microscopytriglyceridetumor necrosis factor αtype 2 diabetes mellitusγ-Glutamylcysteine ligase
主题词
动物(Animals);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);抗氧化剂(Antioxidants);血糖(Blood Glucose);体重(Body Weight);细胞因子类(Cytokines);糖尿病, 实验性(Diabetes Mellitus, Experimental);糖尿病, 2型(Diabetes Mellitus, Type 2);糖原异生(Gluconeogenesis);降血脂药物(Hypolipidemic Agents);注射, 腹腔内(Injections, Intraperitoneal);胰岛素(Insulin);胰岛素抗药性(Insulin Resistance);脂类代谢(Lipid Metabolism);肝(Liver);男(雄)性(Male);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);齐墩果酸(Oleanolic Acid);器官测量(Organ Size);活性氧(Reactive Oxygen Species)
DOI
10.1016/j.mce.2013.06.014
PMID
23791844
发布时间
2022-03-30
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