换一批
换一批The helical propensity of KLA amphipathic peptides enhances their binding to gel-state lipid membranes.
作者：
关键词
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerolAlaAlanineAntimicrobial peptideApparent binding constantCDCircular dichroism spectroscopyConstant pressure heat capacity changeDLSDPPCDPPEDPPGDSCDifferential scanning calorimetryDynamic light scatteringFDAFood and Drug AdministrationITCIsothermal titration calorimetryK(app)L/PLUVsLarge unilamellar vesiclesLeuLeucineLipid peptide ratioLipid–peptide interactionLysLysineMICMain phase transition temperatureMinimum inhibitory concentrationNPCPEPGPOPCPOPGPeptide helicityPhosphatidylcholinePhosphatidylethanolaminePhosphatidylglycerolRBCRed blood cellsSUVsSmall unilamellar vesiclesStandard enthalpy changeStandard entropy change, ΔGo, Standard free energy changeStoichiometryStructure–activity relationshipT(m)TFETrifluoroethanolTrpTryptophanΔC(p)ΔHoΔSo
主题词
氨基酸序列(Amino Acid Sequence);量热法, 差式扫描(Calorimetry, Differential Scanning);圆二色性(Circular Dichroism);凝胶类(Gels);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);光(Light);脂双层(Lipid Bilayers);肽类(Peptides);磷脂酰甘油类(Phosphatidylglycerols);蛋白质结构, 二级(Protein Structure, Secondary);散射, 辐射(Scattering, Radiation);静电(Static Electricity);构效关系(Structure-Activity Relationship);温度(Temperature)
DOI
10.1016/j.bpc.2013.05.003
PMID
23792704
发布时间
2019-12-10
- 浏览80
Biophysical chemistry
10-21页
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