Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules.-论文-万方医学网

作者： Jessica L,Childs-Disney ^[1] ; Ewa,Stepniak-Konieczna ; Tuan,Tran ; Ilyas,Yildirim ; HaJeung,Park ; Catherine Z,Chen ; Jason,Hoskins ; Noel,Southall ; Juan J,Marugan ; Samarjit,Patnaik ; Wei,Zheng ; Chris P,Austin ; George C,Schatz ; Krzysztof,Sobczak ; Charles A,Thornton ; Matthew D,Disney

作者单位： Department of Chemistry, The Scripps Research Institute, Scripps Florida, 130 Scripps Way #3A1, Jupiter, Florida 33458, USA. ^[1]

主题词动物(Animals);碱基序列(Base Sequence);外显子(Exons);成纤维细胞(Fibroblasts);基因敲低技术(Gene Knockdown Techniques);HEK293细胞(HEK293 Cells);高通量筛选分析(High-Throughput Screening Assays);人类(Humans);小鼠(Mice);分子序列数据(Molecular Sequence Data);营养不良性肌强直(Myotonic Dystrophy);质粒(Plasmids);蛋白质结合(Protein Binding);蛋白质生物合成(Protein Biosynthesis);RNA(RNA);RNA前体(RNA Precursors);RNA剪接(RNA Splicing);RNA结合蛋白质类(RNA-Binding Proteins);受体, 胰岛素(Receptor, Insulin);小分子化合物库(Small Molecule Libraries)

DOI 10.1038/ncomms3044

PMID 23806903

发布时间 2021-10-21

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Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules.

Nature communications

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Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules.

Nature communications

相似文献

Nature communications

相关期刊

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