换一批Sp-2-propylthio-ATP-α-B and Sp-2-propylthio-ATP-α-B,β-γ-dichloromethylene are novel potent and specific agonists of the human P2Y₁₁ receptor.
第一作者：
Michael,Haas
第一单位：
Institute for Neurobiochemistry, Faculty of Medicine, Otto-von-Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.
作者：
关键词
2-MeS-ATP2-methylthio-adenosine-5′-triphosphate2-propylthio-ATP-β-γ-dichloromethylene3′-O-(4-benzoylbenzoyl)adenosine-5′-triphosphateADPADPβSAR-C67085ATPATPγSBzATPIBMXIP(3)Nucleotide receptorP2Y receptorPurinergic agonistUTPUTRadenosine-5′(2-thio)diphosphateadenosine-5′(3-thio)-triphosphateadenosine-5′-diphosphateadenosine-5′-triphosphatedATPdesoxy-adenosine-5′-triphosphatee-NTPDaseecto-nucleoside-triphosphate-diphosphohydrolaseinositol-1,4,5-trisphosphateisobutyl-methyl-xanthineuntranslated regionuridine-5′-triphosphate
医学主题词
腺苷三磷酸(Adenosine Triphosphate);细胞系, 肿瘤(Cell Line, Tumor);人类(Humans);多态性, 单核苷酸(Polymorphism, Single Nucleotide);嘌呤能P2受体激动剂(Purinergic P2 Receptor Agonists);受体, 嘌呤能P2(Receptors, Purinergic P2)
DOI
10.1016/j.bcp.2013.06.013
PMID
23810430
发布时间
2013-11-21
- 浏览174
Biochemical pharmacology
645-55页
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